Before high-sensitivity troponin, which MI marker did your lab rely on, CK-MB mass or index, and what threshold did you use? At my last site in 2011 we flagged CK-MB index >2.5% with a 0/3-hour draw schedule and documented a read-back call to ED within 10 minutes to keep reporting precise and timely.
On the ADA front, the quickest win for us was keeping native focus outlines and bumping contrast; swapping one brand color after a WebAIM check WebAIM: Contrast Checker fixed half our issues. I still sketch on a 960-ish column to think in fractions, but ship fluid with CSS Grid and clamp(), since fixed widths make keyboard testing a pain — kind of like fogged lab goggles. If you’re stuck on legacy 960, at least set a max-width container and let gutters scale.
We ran CK-MB mass with an index backup: “mass >5 ng/mL or index >3%” positive, and we did 0/3/6-hour draws with a 10-minute critical callback — felt like speed-dating with the ED phones. For borderline cases we relied on a delta, >1.6 ng/mL at 3 hours, and noted interferences from skeletal muscle injury or renal failure. Curious if you ever paired myoglobin for the early window or stuck strictly to CK-MB?
Quick example: we set CK‑MB mass positive at >4 ng/mL, but only calculated/used the index when total CK was >100 U/L to avoid inflated percentages from low CK, and we required a ‘delta >20%’ across 0/3‑hour draws — @kendraL56 did you gate the index like that?