Maintaining the quality of tissue samples is crucial for accurate lab results. Recently, I started using a new embedding technique that really improved the integrity of our samples. I’ve noticed fewer artifacts when sectioning, which is a huge time-saver. I’d love to hear what methods others are exploring or any tips for maintaining our equipment in the process.
I’ve had success with using a low-temperature embedding medium to enhance clarity — agree on the maintenance aspect — cleaning the microtome blades regularly has really helped us minimize artifacts. What embedding medium are you using?
I’ve found that using a paraffin alternative can really help prevent those pesky artifacts too. It’s like switching from a clunky old car to a smooth ride — much easier to manage! What kind of maintenance routines do you have for your microtome, @gillianT_902?